IgG anti-IgG antibodies in rheumatoid arthritis and certain other conditions.
نویسندگان
چکیده
منابع مشابه
IgG anti-IgG antibodies in rheumatoid arthritis and certain other conditions.
Rheumatoid factor (Rose, Ragan, Pearce, and Lipman, 1948), known to be a frequent finding in the sera of patients with rheumatoid arthritis, was thought to be an unusual antibody in that it occurred in the 19S and 22S forms (Franklin, Holman, Muller-Eberhard, and Kunkel, 1957) without showing evidence for 7S analogues. The activity of this antibody appeared to be directed against gammaglobulin....
متن کاملIgG and IgA antibodies to mycobacterial antigens in rheumatoid arthritis
Autoantigens cross reactive with mycobacteria are implicated in the pathogenesis of adjuvant arthritis in the rat, and there are reports of changes in the immune response to mycobacteria in human rheumatoid arthritis (RA). We have therefore examined the IgM, IgG, and IgA antibody levels to crude mycobacterial antigens and to two recombinant mycobacterial heat shock/stress proteins (65 kD and 71...
متن کاملAnti-myeloperoxidase antibodies in patients with rheumatoid arthritis: prevalence, clinical correlates, and IgG subclass.
OBJECTIVES To determine the prevalence and clinical associations of autoantibodies to myeloperoxidase (MPO) in an unselected series of well-characterised outpatients with rheumatoid arthritis (RA) and to compare the distribution of IgG subclasses of anti-MPO antibodies in these patients with that in patients with systemic vasculitis. PATIENTS AND METHODS A study was made of 97 patients with R...
متن کاملThe isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients
BACKGROUND Anti-carbamylated protein (anti-CarP) antibodies have recently been reported to occur in around 45% of rheumatoid arthritis (RA) patients and to have prognostic and diagnostic properties. At present, the breadth and molecular make-up of the anti-CarP antibody response is ill defined. To understand the anti-CarP antibody immune response and potential immune effector mechanisms it can ...
متن کاملA new antibody in rheumatoid arthritis targeting glycated IgG: IgM anti-IgG-AGE.
Hyperglycaemia and/or oxidative stress can cause IgG to be modified by advanced glycation end products (AGE). Three patients with aggressive rheumatoid arthritis (RA) and vasculitis are described who have high titres of IgM antibodies against AGE-modified IgG (IgM anti-IgG-AGE). Diabetics and randomly selected patients with rheumatic diseases, including 50 additional RA patients, were tested fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1974
ISSN: 0003-4967
DOI: 10.1136/ard.33.3.258